Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry

Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions. Although their transfection efficiency has been pro...

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Bibliographic Details
Main Authors: Emma-Dune Leriche, Marie Hubert-Roux, Carlos Afonso, Catherine M. Lange, Martin C. Grossel, Florian Maire, Corinne Loutelier-Bourhis
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Molecules
Subjects:
polyamidoamine dendrimers
oligonucleotide duplex
dendriplexes
electrospray mass spectrometry
tandem mass spectrometry
ion mobility spectrometry
Online Access:http://www.mdpi.com/1420-3049/19/12/20731

Internet

http://www.mdpi.com/1420-3049/19/12/20731

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