Development of Glutathione Production Technology Based on Constructed Active Yeast Overproducers

Recombinant Hansenula polymorpha strain overexpressing both GSH2 gene, encoding γ-glutamylcysteine synthetase, and MET4 gene, coding for transcription activator of genes involved in cysteine biosynthesis (precursor of glutathione) was obtained applying metabolic engineering approaches. Obtained reco...

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Bibliographic Details
Main Authors: Yurkiv M.T., Kurylenko O.O., Vasylyshyn R.V., Dmytruk K.V., Martynyuk N.B., Skorohod V.V., Sybirny A.A.
Format: Article
Language:Ukrainian
Published: Publishing House "Akademperiodyka" 2015-09-01
Series:Nauka ta Innovacii
Subjects:
Online Access:ftp://nas.gov.ua/akademperiodyka/Downloads/Archive%20SI%20Journal/SI_ukr/2015/N5/Yurkiv.pdf