Quantitative Structure – Pharmacokinetics Relationships Analysis of Basic Drugs: Volume of Distribution

Purpose. The early prediction of pharmacokinetic behavior is of paramount importance for saving time and resources and for increasing the success of new drug candidates. The steady-state volume of distribution (VDss) is one of the key pharmacokinetic parameters required for the design of a suitable...

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Bibliographic Details
Main Authors: Zvetanka Dobreva Zhivkova, Tsvetelina Mandova, Irini Doytchinova
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2015-10-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/24772