Impaired resolution of DSS-induced colitis in mice lacking the glucocorticoid receptor in myeloid cells.

Inflammatory bowel disease (IBD) is a highly prevalent intestinal disorder for which no cure exists. Currently, the standard first-line treatment of IBD consists of systemic glucocorticoid (GC) application, even though therapy can be complicated by unresponsiveness or adverse effects. In view of the...

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Bibliographic Details
Main Authors: Garrit K Meers, Hanibal Bohnenberger, Holger M Reichardt, Fred Lühder, Sybille D Reichardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5764312?pdf=render