ChIPnorm: a statistical method for normalizing and identifying differential regions in histone modification ChIP-seq libraries.

The advent of high-throughput technologies such as ChIP-seq has made possible the study of histone modifications. A problem of particular interest is the identification of regions of the genome where different cell types from the same organism exhibit different patterns of histone enrichment. This p...

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Bibliographic Details
Main Authors: Nishanth Ulhas Nair, Avinash Das Sahu, Philipp Bucher, Bernard M E Moret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411705?pdf=render