Synthesis and preliminary hepatotoxicity evaluation of new caffeine-8-(2-thio)-propanoic hydrazid-hydrazone derivatives

New series of caffeine-8-(2-thio)-propanoic hydrazid-hydrazone derivatives were designed and synthesized. The targed compounds were obtained in yields of 51 to 96% and their structures were elucidated by FTIR, 1H NMR, 13C NMR, MS and microanalyses. All of the compounds were found t...

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Bibliographic Details
Main Authors: Javor Mitkov, Magdalena Kondeva-Burdina, Alexander Zlatkov
Format: Article
Language:English
Published: Pensoft Publishers 2019-10-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/37263/download/pdf/