Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application
Abstract Connexin, a four-pass transmembrane protein, contributes to assembly of gap junctions among neighboring cells and thus facilitates gap junctional intercellular communication (GJIC). Traditionally, the roles of connexins were thought to mediate formation of hemichannels and GJIC assembly for...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-01-01
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| Series: | Journal of Biomedical Science |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12929-019-0497-x |