Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

Summary: Hippocampal Lewy body pathology (LBP) is associated with changes in neurotrophic factor signaling and neuronal energy metabolism. LBP progression is attributed to the aggregation of α-synuclein (α-Syn) and its cell-to-cell transmission via extracellular vehicles (EVs). We recently discovere...

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Bibliographic Details
Main Authors: Rohit Kumar, Sainitin Donakonda, Stephan A. Müller, Stefan F. Lichtenthaler, Kai Bötzel, Günter U. Höglinger, Thomas Koeglsperger
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:iScience
Subjects:
Biological Sciences
Molecular Neuroscience
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305368

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http://www.sciencedirect.com/science/article/pii/S2589004220305368

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