A Comparison of Automated Perfusion- and Manual Diffusion-Based Human Regulatory T Cell Expansion and Functionality Using a Soluble Activator Complex
Absence or reduced frequency of human regulatory T cells (Tregs) can limit the control of inflammatory responses, autoimmunity, and the success of transplant engraftment. Clinical studies indicate that use of Tregs as immunotherapeutics would require billions of cells per dose. The Quantum® Cell Exp...
Main Authors: | Mark Jones, Brian Nankervis, Kelly Santos Roballo, Huong Pham, Jared Bushman, Claire Coeshott |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-05-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/0963689720923578 |
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