A Comparison of Automated Perfusion- and Manual Diffusion-Based Human Regulatory T Cell Expansion and Functionality Using a Soluble Activator Complex

Absence or reduced frequency of human regulatory T cells (Tregs) can limit the control of inflammatory responses, autoimmunity, and the success of transplant engraftment. Clinical studies indicate that use of Tregs as immunotherapeutics would require billions of cells per dose. The Quantum® Cell Exp...

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Bibliographic Details
Main Authors: Mark Jones, Brian Nankervis, Kelly Santos Roballo, Huong Pham, Jared Bushman, Claire Coeshott
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720923578