Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response.

Aberrant glycosylation of mucins and other extracellular proteins is an important event in carcinogenesis and the resulting cancer associated glycans have been suggested as targets in cancer immunotherapy. We assessed the role of O-linked GalNAc glycosylation on antigen uptake, processing, and prese...

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Bibliographic Details
Main Authors: Caroline B Madsen, Cecilie Petersen, Kirstine Lavrsen, Mikkel Harndahl, Søren Buus, Henrik Clausen, Anders E Pedersen, Hans H Wandall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23189185/?tool=EBI