Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels

The aim of this study was to characterize two monoclonal antibodies (F6A11 and F109-D12) generated against Pdx1 (pancreatic and duodenal homeobox-1), a homeodomain transcription factor, which is critical for pancreas formation as well as for normal pancreatic beta cell function. For production of mo...

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Bibliographic Details
Main Authors: T. Galbo, I. L Pedersen, T. Fløyel, C. H. Bang-Berthelsen, P. Serup, O. D Madsen, J. Hald
Format: Article
Language:English
Published: PAGEPress Publications 2010-04-01
Series:European Journal of Histochemistry
Subjects:
Dox
Online Access:http://www.ejh.it/index.php/ejh/article/view/1676