Generalization of Wei's urn design to unequal allocations in sequential clinical trials
Wei's urn design was proposed in 1987 for subject randomization in trials comparing m≥2 treatments with equal allocation. In this manuscript, two modified versions of Wei's urn design are presented to accommodate unequal allocations. First one uses a provisional allocation of r12:r22 to ac...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-04-01
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| Series: | Contemporary Clinical Trials Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865415300478 |