Neuroprotectants attenuate hypobaric hypoxia-induced brain injuries in cynomolgus monkeys

Neuroprotectants attenuate hypobaric hypoxia-induced brain injuries in cynomolgus monkeys

Hypobaric hypoxia (HH) exposure can cause serious brain injury as well as life-threatening cerebral edema in severe cases. Previous studies on the mechanisms of HH-induced brain injury have been conducted primarily using non-primate animal models that are genetically distant to humans, thus hinderin...

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Bibliographic Details
Main Authors: Pei Zhang, Jie-Si Chen, Qi-Ye Li, Long-Xiang Sheng, Yi-Xing Gao, Bing-Zheng Lu, Wen-Bo Zhu, Xiao-Yu Zhan, Yuan Li, Zhi-Bing Yuan, Gang Xu, Bi-Tao Qiu, Min Yan, Chun-Xue Guo, You-Qiong Wang, Yi-Jun Huang, Jing-Xia Zhang, Fu-Yu Liu, Zhong-Wei Tang, Sui-Zhen Lin, David N. Cooper, Huan-Ming Yang, Jian Wang, Yu-Qi Gao, Wei Yin, Guo-Jie Zhang, Guang-Mei Yan
Format: Article
Language:English
Published: Science Press, PR China 2020-01-01
Series:Zoological Research
Subjects:
acute hypobaric hypoxia
cynomolgus monkeys
brain injury
neuroprotectant
gene regulatory networks
Online Access:http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.012

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http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.012

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