Dynamics and Regulation of RecA Polymerization and De-Polymerization on Double-Stranded DNA.

The RecA filament formed on double-stranded (ds) DNA is proposed to be a functional state analogous to that generated during the process of DNA strand exchange. RecA polymerization and de-polymerization on dsDNA is governed by multiple physiological factors. However, a comprehensive understanding of...

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Bibliographic Details
Main Authors: Hongxia Fu, Shimin Le, Kalappa Muniyappa, Jie Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688958?pdf=render