Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway

Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway

The naturally occurring isothiocyanate sulforaphane, found in vegetables, shows promising anti-inflammatory, anti-apoptosis, and anti-oxidative effects. Whether sulforaphane protects against lipopolysaccharide (LPS)-induced injury in intestinal epithelial cells is unclear. The present study examines...

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Bibliographic Details
Main Authors: Yu-jie Zhang, Qian Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
sulforaphane
intestinal epithelial cells
oxidative stress
apoptosis
inflammation
ampk/sirt1/pgc-1ɑ pathway
Online Access:http://dx.doi.org/10.1080/21655979.2021.1952368

Internet

http://dx.doi.org/10.1080/21655979.2021.1952368

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