Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
<p>Abstract</p> <p>Background</p> <p>Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selection methods are limited by uncertainties in RNA secondary structu...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-03-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/7/122 |