The Molecular Evolutionary Patterns of the Insulin/FOXO Signaling Pathway

The insulin/insulin growth factor-1 (IGF1)/FOXO (IIF) signal transduction pathway plays a core role in the endocrine system. Although the components of this pathway have been well characterized, the evolutionary pattern remains poorly understood. Here, we perform a comprehensive analysis to study wh...

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Bibliographic Details
Main Authors: Minghui Wang, Qishan Wang, Zhen Wang, Qingping Wang, Xiangzhe Zhang, Yuchun Pan
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S10539