Vascular Dysfunction as Target Organ Damage in Animal Models of Hypertension

Endothelial dysfunction is one of the main characteristics of chronic hypertension and it is characterized by impaired nitric oxide (NO) bioactivity determined by increased levels of reactive oxygen species. Endothelial function is usually evaluated by measuring the vasodilation induced by the local...

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Bibliographic Details
Main Authors: Mario Fritsch Neves, Daniel Arthur B. Kasal, Ana Rosa Cunha, Fernanda Medeiros
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2012/187526