Hypoxia-Induced Adipose Lipolysis Requires Fibroblast Growth Factor 21

Fibroblast growth factor 21 (FGF21) is a recently discovered hepatokine that regulates lipid and glucose metabolism and is upregulated in response to numerous physiological and pathological stimuli. Herein, we demonstrate that both physical and chemical hypoxia increase the systemic and hepatic expr...

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Bibliographic Details
Main Authors: Guicheng Wu, Yanlong Liu, Wenke Feng, Xuan An, Wenhui Lin, Chengwei Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01279/full