Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging
TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.
Main Authors: | Anna Archetti, Evgenii Glushkov, Christian Sieben, Anton Stroganov, Aleksandra Radenovic, Suliana Manley |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09247-1 |
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