Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.

Bibliographic Details
Main Authors: Anna Archetti, Evgenii Glushkov, Christian Sieben, Anton Stroganov, Aleksandra Radenovic, Suliana Manley
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09247-1