KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression

KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression

Background/Aims: Angiotensin II (Ang II) has been regarded as an important profibrogenic cytokine in renal fibrosis. Krüppel-like factor 15 (KLF15) has been identified as an important negative transcription factor in renal fibrosis. However, little is known about the role of KLF15 in Ang II-induced...

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Bibliographic Details
Main Authors: Xiangchen Gu, Dechao Xu, Lili Fu, Yi Wang, Changlin Mei, Xiang Gao
Format: Article
Language:English
Published: Karger Publishers 2017-11-01
Series:Kidney & Blood Pressure Research
Subjects:
Angiotensin II
Krüppel-like factor 15
Connective tissue growth factor
Renal fibrosis
P/CAF
Online Access:https://www.karger.com/Article/FullText/485349

Internet

https://www.karger.com/Article/FullText/485349

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