A novel Gynostemma pentaphyllum saponin and its adipogenesis inhibitory effect through modulating Wnt/β-catenin pathway and cell cycle in mitotic clonal expansion

A novel saponin (JS) was isolated from the tetraploid jiaogulan, a popular tea also known as Gynostemma pentaphyllum, and characterized for its chemical structure. JS was investigated for its inhibitory effect on adipocyte differentiation and the potential molecular mechanisms using 3T3-L1 murine pr...

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Bibliographic Details
Main Authors: Jie Liu, Puyu Yang, Haiming Shi, Xiangjun Sun, Seong-Ho Lee, Liangli (Lucy) Yu
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615002984