Radiation Damage Mechanisms of Chemotherapeutically Active Nitroimidazole Derived Compounds

Radiation Damage Mechanisms of Chemotherapeutically Active Nitroimidazole Derived Compounds

Photoionization mass spectrometry, photoelectron-photoion coincidence spectroscopic technique, and computational methods have been combined to investigate the fragmentation of two nitroimidazole derived compounds: the metronidazole and misonidazole. These molecules are used in radiotherapy thanks to...

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Bibliographic Details
Main Authors: Jacopo Chiarinelli, Anna Rita Casavola, Mattea Carmen Castrovilli, Paola Bolognesi, Antonella Cartoni, Feng Wang, R. Richter, Daniele Catone, Sanja Tosic, Bratislav P. Marinkovic, Lorenzo Avaldi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Chemistry
Subjects:
nitroimidazole
radiosensitizers
mass spectrometry
PEPICO experiments
appearance energy
DFT
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00329/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00329/full

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