ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux

Apolipoproteins, such as apolipoprotein A-I (apoA-I), can stimulate cholesterol efflux from cells expressing the ATP binding cassette transporter A1 (ABCA1). The nature of the molecular interaction between these cholesterol acceptors and ABCA1 is controversial, and models suggesting a direct protein...

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Bibliographic Details
Main Authors: M.L. Fitzgerald, A.L. Morris, A. Chroni, A.J. Mendez, V.I. Zannis, M.W. Freeman
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319003