Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3.

Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3.

Angelman syndrome (AS) is a neurobehavioral disorder associated with mental retardation, absence of language development, characteristic electroencephalography (EEG) abnormalities and epilepsy, happy disposition, movement or balance disorders, and autistic behaviors. The molecular defects underlying...

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Bibliographic Details
Main Authors: Yong-Hui Jiang, Yanzhen Pan, Li Zhu, Luis Landa, Jong Yoo, Corinne Spencer, Isabel Lorenzo, Murray Brilliant, Jeffrey Noebels, Arthur L Beaudet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2924885?pdf=render

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http://europepmc.org/articles/PMC2924885?pdf=render

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