Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions
<p>Abstract</p> <p>Background</p> <p>The goal of linkage analysis is to determine the chromosomal location of the gene(s) for a trait of interest such as a common disease. Three-locus linkage analysis is an important case of multi-locus problems. Solutions can be found...
Main Authors: | Guo Jianhua, Fung Wing-Kam, Shi Ning-Zhong, Zhou Ying |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-01-01
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Series: | BMC Genetics |
Online Access: | http://www.biomedcentral.com/1471-2156/9/1 |
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