Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions
<p>Abstract</p> <p>Background</p> <p>The goal of linkage analysis is to determine the chromosomal location of the gene(s) for a trait of interest such as a common disease. Three-locus linkage analysis is an important case of multi-locus problems. Solutions can be found...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-01-01
|
| Series: | BMC Genetics |
| Online Access: | http://www.biomedcentral.com/1471-2156/9/1 |