Importance of radiolytic reactions during high-LET irradiation modalities: LET effect, role of O2 and radiosensitization by nanoparticles

Importance of radiolytic reactions during high-LET irradiation modalities: LET effect, role of O2 and radiosensitization by nanoparticles

Abstract This article reviews radiation chemistry processes induced by high-linear energy transfer (LET) radiation. The first part gives a short historical introduction and defines the essential concepts of radiation chemistry. It is aimed at radiobiologists in search of basics in this discipline, t...

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Bibliographic Details
Main Authors: Gérard Baldacchino, Emilie Brun, Ibtihel Denden, Sarah Bouhadoun, Raphael Roux, Hicham Khodja, Cécile Sicard-Roselli
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cancer Nanotechnology
Subjects:
Radiation chemistry
Linear energy transfer (LET) effect
Reactive oxygen species (ROS)
Relative biological effectiveness (RBE)
Oxygen enhancement ratio (OER)
Radiosensitization
Online Access:http://link.springer.com/article/10.1186/s12645-019-0047-y

Internet

http://link.springer.com/article/10.1186/s12645-019-0047-y

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