αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish

Cadherin complexes mediate cell-cell adhesion and are crucial for embryonic development. Besides their structural function, cadherin complexes also transduce tension across the junction-actomyosin axis into proportional biochemical responses. Central to this mechanotransduction is the stretching of...

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Bibliographic Details
Main Authors: Mitchell K. L. Han, Esteban Hoijman, Emily Nöel, Laurence Garric, Jeroen Bakkers, Johan de Rooij
Format: Article
Language:English
Published: The Company of Biologists 2016-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/10/1461