Cyclic stretch facilitates myogenesis in C2C12 myoblasts and rescues thiazolidinedione-inhibited myotube formation

Cyclic stretch facilitates myogenesis in C2C12 myoblasts and rescues thiazolidinedione-inhibited myotube formation

Thiazolidinedione (TZD), a specific peroxisome proliferator-activated receptor r (PPARr) agonist, was developed to control blood glucose in diabetes patients. However, several side effects were reported that increased the risk of heart failure. We used C2C12 myoblasts to investigate the role of PPAR...

Full description

Bibliographic Details
Main Authors: Ya-Ju eChang, Yun-Ju eChen, Chia-Wei eHuang, Shih-Chen eFan, Bu-Miin eHuang, Wen-Tsang eChang, Yau-Sheng eTsai, Fong-Chin eSu, Chia-Ching eWu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
myogenesis
PPAR
stretch
C2C12
Myotube formation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2016.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2016.00027/full

Similar Items