Propensity score to detect baseline imbalance in cluster randomized trials: the role of the c-statistic

Abstract Background Despite randomization, baseline imbalance and confounding bias may occur in cluster randomized trials (CRTs). Covariate imbalance may jeopardize the validity of statistical inferences if they occur on prognostic factors. Thus, the diagnosis of a such imbalance is essential to adj...

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Bibliographic Details
Main Authors: Clémence Leyrat, Agnès Caille, Yohann Foucher, Bruno Giraudeau
Format: Article
Language:English
Published: BMC 2016-01-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-015-0100-4