Mink SLAM V-Region V74I Substitutions Contribute to the Formation of Syncytia Induced by Canine Distemper Virus

Mink SLAM V-Region V74I Substitutions Contribute to the Formation of Syncytia Induced by Canine Distemper Virus

The Signal lymphatic activation molecule (SLAM, also known as CD150) as the cellular receptor of canine distemper virus (CDV) plays an important role in the virus-host interaction. However, it is still unknown whether amino acid differences in the SLAM variable (V) region affect the formation of syn...

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Bibliographic Details
Main Authors: Yawen Wang, Jie Chen, Bo Hu, Chengyan Gong, Ning Shi, Mengjia Liu, Xijun Yan, Xue Bai, Jianjun Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Veterinary Science
Subjects:
canine distemper virus
signaling lymphocyte activation molecule
hemagglutinin protein
syncytia
variable region
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.570283/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.570283/full

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