Correlated evolution of nucleotide substitution rates and allelic variation in <it>Mhc-DRB </it>lineages of primates
<p>Abstract</p> <p>Background</p> <p>The major histocompatibility complex (MHC) is a key model of genetic polymorphism. Selection pressure by pathogens or other microevolutionary forces may result in a high rate of non-synonymous substitutions at the codons specifying t...
Main Authors: | de Groot Natasja G, Garamszegi László Z, Bontrop Ronald E |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-04-01
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Series: | BMC Evolutionary Biology |
Online Access: | http://www.biomedcentral.com/1471-2148/9/73 |
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