Correlated evolution of nucleotide substitution rates and allelic variation in <it>Mhc-DRB </it>lineages of primates

<p>Abstract</p> <p>Background</p> <p>The major histocompatibility complex (MHC) is a key model of genetic polymorphism. Selection pressure by pathogens or other microevolutionary forces may result in a high rate of non-synonymous substitutions at the codons specifying t...

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Bibliographic Details
Main Authors: de Groot Natasja G, Garamszegi László Z, Bontrop Ronald E
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/73