DMD transcripts in CRL-2061 rhabdomyosarcoma cells show high levels of intron retention by intron-specific PCR amplification

DMD transcripts in CRL-2061 rhabdomyosarcoma cells show high levels of intron retention by intron-specific PCR amplification

Abstract Background The DMD gene encoding dystrophin is mutated in Duchenne muscular dystrophy, a fatal progressive muscle wasting disease. DMD has also been shown to act as a tumor suppressor gene. Rhabdomyosarcoma (RMS) is a mesodermal sarcoma that shares characteristics of skeletal muscle precurs...

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Bibliographic Details
Main Authors: Emma Tabe Eko Niba, Ryo Yamanaka, Abdul Qawee Mahyoob Rani, Hiroyuki Awano, Masaaki Matsumoto, Hisahide Nishio, Masafumi Matsuo
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Cancer Cell International
Subjects:
DMD
Intron retention
Rhabdomyosarcoma
Tumor suppressor
Online Access:http://link.springer.com/article/10.1186/s12935-017-0428-4

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http://link.springer.com/article/10.1186/s12935-017-0428-4

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