Structure Prediction of Human Fatty Acid Synthase–Dehydratase: A Plausible Model for Understanding Active Site Interactions
Fatty acid synthase (FASN, UniProt ID: P49327) is a multienzyme dimer complex that plays a critical role in lipogenesis. Consequently, this lipogenic enzyme has gained tremendous biomedical importance. The role of FASN and its inhibition is being extensively researched in several clinical conditions...
Main Authors: | Arun John, Vetrivel Umashankar, A. Samdani, Manoharan Sangeetha, Subramanian Krishnakumar, Perinkulam Ravi Deepa |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | Bioinformatics and Biology Insights |
Online Access: | https://doi.org/10.4137/BBI.S38317 |
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