Structure Prediction of Human Fatty Acid Synthase–Dehydratase: A Plausible Model for Understanding Active Site Interactions

Fatty acid synthase (FASN, UniProt ID: P49327) is a multienzyme dimer complex that plays a critical role in lipogenesis. Consequently, this lipogenic enzyme has gained tremendous biomedical importance. The role of FASN and its inhibition is being extensively researched in several clinical conditions...

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Bibliographic Details
Main Authors: Arun John, Vetrivel Umashankar, A. Samdani, Manoharan Sangeetha, Subramanian Krishnakumar, Perinkulam Ravi Deepa
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S38317