Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets.

The acquisition of neuraminidase (NA) inhibitor resistance by H5N1 influenza viruses has serious clinical implications, as this class of drugs can be an essential component of pandemic control measures. The continuous evolution of the highly pathogenic H5N1 influenza viruses results in the emergence...

Full description

Bibliographic Details
Main Authors: Natalia A Ilyushina, Jon P Seiler, Jerold E Rehg, Robert G Webster, Elena A Govorkova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2877746?pdf=render