Reverse Engineering of Vaccine Antigens Using High Throughput Sequencing-enhanced mRNA Display

Vaccine reverse engineering is emerging as an important approach to vaccine antigen identification, recently focusing mainly on structural characterization of interactions between neutralizing monoclonal antibodies (mAbs) and antigens. Using mAbs that bind unknown antigen structures, we sought to pr...

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Bibliographic Details
Main Authors: Nini Guo, Hongying Duan, Alla Kachko, Benjamin W. Krause, Marian E. Major, Philip R. Krause
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300517