Proteomic analysis of detergent resistant membrane domains during early interaction of macrophages with rough and smooth Brucella melitensis.

The plasma membrane contains discrete nanometer-sized domains that are resistant to non-ionic detergents, and which are called detergent resistant membrane domains (DRMDs) or lipid rafts. Exposure of host cells to pathogenic bacteria has been shown to induce the re-distribution of specific host prot...

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Bibliographic Details
Main Authors: Sabine A Lauer, Srinivas Iyer, Timothy Sanchez, Christian V Forst, Brent Bowden, Kay Carlson, Nammalwar Sriranganathan, Stephen M Boyle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958395?pdf=render