Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.

The HOXB13 germline variant G84E (rs138213197) was recently described in men of European descent, with the highest prevalence in Northern Europe. The G84E mutation has not been found in patients of African or Asian ancestry, which may carry other HOXB13 variants, indicating allelic heterogeneity dep...

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Bibliographic Details
Main Authors: Sofia Maia, Marta Cardoso, Pedro Pinto, Manuela Pinheiro, Catarina Santos, Ana Peixoto, Maria José Bento, Jorge Oliveira, Rui Henrique, Carmen Jerónimo, Manuel R Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0132728