Critical Role of Alternative M2 Skewing in miR-155 Deletion-Mediated Protection of Colitis

Critical Role of Alternative M2 Skewing in miR-155 Deletion-Mediated Protection of Colitis

Inflammatory bowel disease (IBD) is associated with dysregulation of both innate and adaptive immune response in the intestine. MicroRNA (miR)-155 is frequently expressed and functions in many immune cell types. Besides its function in adaptive immunity, miR-155 is a key regulator of the innate immu...

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Bibliographic Details
Main Authors: Jintao Li, Ji Zhang, Hongxia Guo, Shimin Yang, Weiping Fan, Nan Ye, Zhiqiang Tian, Tiantian Yu, Guoping Ai, Zigang Shen, Haiyang He, Ping Yan, Hui Lin, Xue Luo, Hongli Li, Yuzhang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
M2 macrophages
miR-155
colitis
C/EBPβ
SOCS1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.00904/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.00904/full

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