Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

Niemöller et al. describe a bisulfite-free assay to assess epigenomics and genomics of single cells (epi-gSCAR). epi-gSCAR generates accurate and reproducible measurements of global DNA methylation and genetic variants at the single cell level, allowing for in-depth analyses of cell-to-cell heteroge...

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Bibliographic Details
Main Authors: Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus, Nathalie Renz, Janika Rhein, Sabine Bleul, Juliane M. Stosch, Justus Duyster, Christoph Plass, Pavlo Lutsik, Daniel B. Lipka, Michael Lübbert, Heiko Becker
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01661-w

Internet

https://doi.org/10.1038/s42003-021-01661-w

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