Comparison of Fetal Porcine Aggregates of Purified β-Cells versus Islet-Like Cell Clusters as a Treatment of Diabetes

Fetal pig islet-like cell clusters (ICCs) have the potential to reverse diabetes 1–5 months after transplantation. In a fetal ICC, however, β-cells constitute only 6–8% of the cells, in contrast to 65% in an adult pig islet. Attempts to purify fetal β-cells from cell clusters and compare their funct...

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Bibliographic Details
Main Authors: Jian Tu, Pauline Khoury, Lindy Williams, Bernard E. Tuch M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2004-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004783983693