A carotenoid-enriched extract from pumpkin delays cell proliferation in a human chronic lymphocytic leukemia cell line through the modulation of autophagic flux

Chronic lymphocytic leukemia (CLL) is the most frequent form of leukemia in the adult population. From an asymptomatic state, which can lay for years, CLL rapidly evolves becoming fatal. Apoptosis resistance and induction of a protective form of autophagy are possible explanations of the poor respon...

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Bibliographic Details
Main Authors: Stefania Moccia, Maria Russo, Miriana Durante, Marcello S. Lenucci, Giovanni Mita, Gian Luigi Russo
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Current Research in Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590262820300101