Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of <i>N</i>-Alkyl d- and l-Iminosugars

Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of <i>N</i>-Alkyl d- and l-Iminosugars

In the effort to improve the antimicrobial activity of iminosugars, we report the synthesis of lipophilic iminosugars <b>10a–b</b> and <b>11a–b</b> based on the one-pot conjugation of both enantiomeric forms of <i>N</i>-butyldeoxynojirimycin (NBDNJ) and <i>N...

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Bibliographic Details
Main Authors: Anna Esposito, Daniele D’Alonzo, Stefano D’Errico, Eliana De Gregorio, Annalisa Guaragna
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Marine Drugs
Subjects:
lipophilic iminosugars
polymer-supported triphenyl phosphine
cholesterol
antibacterial iminosugars
Online Access:https://www.mdpi.com/1660-3397/18/11/572

Internet

https://www.mdpi.com/1660-3397/18/11/572

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