RIP3 impedes transcription factor EB to suppress autophagic degradation in septic acute kidney injury
Abstract Autophagy is an important renal-protective mechanism in septic acute kidney injury (AKI). Receptor interacting protein kinase 3 (RIP3) has been implicated in the renal tubular injury and renal dysfunction during septic AKI. Here we investigated the role and mechanism of RIP3 on autophagy in...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03865-8 |