RIP3 impedes transcription factor EB to suppress autophagic degradation in septic acute kidney injury

Abstract Autophagy is an important renal-protective mechanism in septic acute kidney injury (AKI). Receptor interacting protein kinase 3 (RIP3) has been implicated in the renal tubular injury and renal dysfunction during septic AKI. Here we investigated the role and mechanism of RIP3 on autophagy in...

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Bibliographic Details
Main Authors: Ruizhao Li, Xingchen Zhao, Shu Zhang, Wei Dong, Li Zhang, Yuanhan Chen, Zhilian Li, Huan Yang, Ying Huang, Zhiyong Xie, Weidong Wang, Chunling Li, Zhiming Ye, Zheng Dong, Xinling Liang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03865-8