Influence of Two Major Toxoplasma Gondii Virulence Factors (ROP16 and ROP18) on the Immune Response of Peripheral Blood Mononuclear Cells to Human Toxoplasmosis Infection

Influence of Two Major Toxoplasma Gondii Virulence Factors (ROP16 and ROP18) on the Immune Response of Peripheral Blood Mononuclear Cells to Human Toxoplasmosis Infection

Toxoplasma gondii ROP16 and ROP18 proteins have been identified as important virulence factors for this parasite. Here, we describe the effect of ROP16 and ROP18 proteins on peripheral blood mononuclear cells (PBMCs) from individuals with different clinical status of infection. We evaluated IFN-γ, I...

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Bibliographic Details
Main Authors: Alejandro Hernández-de-los-Ríos, Mateo Murillo-Leon, Luz Eliana Mantilla-Muriel, Ailan Farid Arenas, Mónica Vargas-Montes, Néstor Cardona, Alejandra de-la-Torre, Juan Carlos Sepúlveda-Arias, Jorge Enrique Gómez-Marín
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
peripheral blood mononuclear cells
Toxoplasma
ROP16 protein
ROP18 protein
ocular toxoplasmosis
cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00413/full

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https://www.frontiersin.org/article/10.3389/fcimb.2019.00413/full

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